Automation
Laboratory Instrumentation

Laboratory Instrumentation White Papers

View white papers from other Pharmaceutical sectors:
91-105 of 240 results
Extending the Boundaries of QbD
| By Malvern Panalytical
The last decade has seen a shift within the pharmaceutical industry towards a design space approach to development and manufacture, an agenda underpinned by ICHQ8, Q9 and Q10 and the concept of Quality by Design (QbD). However, because a design space approach naturally focuses attention on the areas of a project that are potentially the most vulnerable to failure it has broader value for risk management.
Automation > Laboratory Instrumentation > White Papers
Measuring Environmental Impact of Nanomaterial Wastes and Contaminants Using Nanoparticle Tracking Analysis
| By Malvern Panalytical
The increasing number of nanomaterial based consumer products raises concerns about their possible impact on the environment. Suitable methods for their analysis are a particular problem in this regard. This white paper reviews the use of Nanoparticle Tracking Analysis (NTA) in addressing this need.
Automation > Laboratory Instrumentation > White Papers
Assessing Nanoparticle Toxicity in Waste Water using Nanoparticle Tracking Analysis
| By Malvern Panalytical
At the same time as an increasing interest in, and rapid development of, a wide range of materials and products containing nanoscale structures and engineered nanoparticles, awareness has grown that the longer term potential toxic effects of such materials and their potential environmental impact are poorly understood. Existing methods have been assessed and new methods sought by which such materials could be analyzed on a routine basis during development and manufacture.
Automation > Laboratory Instrumentation > White Papers
Growing Potential: mAb Production With Fibra-Cel
| By Eppendorf
The market for monoclonal antibodies continues to grow steadily, but there are still bottlenecks in the development of new products, including long development times mostly due to R&D. Advanced bioprocess equipment that meets the specific demands of mAb-producing hybridoma can accelerate design and production, and reduce overall development costs along the way.
Automation > Laboratory Instrumentation > White Papers
DoE Bioprocess Development
| By Eppendorf
Eppendorf DASware is the effective route to design of experiments (DoE) in early-stage bioprocess development. Claudia M Huether-Franken and Sebastian Kleebank explain how the design software applies DoE to DASGIP parallel bioreactor systems.
Automation > Laboratory Instrumentation > White Papers
NTA: Exosomes and Microvesicles - General
| By Malvern Panalytical
The study of exosomes and other cell-derived microvesicles is an area of rapidly growing importance and the subject of intense interest and research. The previous lack of suitable methods for their detection, analysis, enumeration and phenotyping is proving to be a significant limitation in these studies. This chapter shows the degree to which the technique of NTA is helping to address these problems.
Automation > Laboratory Instrumentation > White Papers
Addressing the Needs of Drug Discovery with the MicroCal PEAQ-ITC Instruments
| By Malvern Panalytical
This white paper highlights the advantages of the new ITC instruments—MicroCal PEAQ-ITC and MicroCal PEAQ-ITC Automated systems and MicroCal PEAQ-ITC Analysis Software. The software allows analysis of binding interactions complicated by the presence of inactive protein material, incorrect protein concentration, and/or inaccurate concentration or heterogeneity of compound solutions.
Automation > Laboratory Instrumentation > White Papers
Use of the new MicroCal PEAQ-ITC System for Measurement and Characterization of a Broad Range of Protein-LMW Compound Interactions
| By Malvern Panalytical
This white paper highlights the beneficial features of the new MicroCal PEAQ-ITC instrument and software for the analysis of binding interactions through direct and competitive titrations.
Automation > Laboratory Instrumentation > White Papers
Important Factors when Buying a Differential Scanning Calorimeter (DSC)
| By Malvern Panalytical
The physical components and features of a Differential Scanning Calorimeter (DSC) instrument and the technical specifications are clearly important to consider when purchasing a new system. However, written specifications can be confusing, misleading and may actually have very little bearing on the actual performance of the instrument. Specifications, on paper, do not necessarily translate into advantages or disadvantages when it comes to making measurements on your samples.
Automation > Laboratory Instrumentation > White Papers
Understanding the Effect of Molecular Weight and Structure on the Performance Characteristics of Cellulose Derivatives using OMNISEC
| By Malvern Panalytical
A key family of molecules of interest to the pharmaceutical industry is those derived from cellulose such as hydroxyethyl cellulose and others. These macromolecules are typically used as viscosity modifiers for various products such as eye drops and moisturizing creams, and as excipients in many other applications.
Automation > Laboratory Instrumentation > White Papers
Forensic Analysis of an Artificial Sweetener Commonly Employed in Hoax Powder Attacks Using Morphologically Directed Raman Spectroscopy
| By Malvern Panalytical
In the wake of the September 11th terrorist attacks, there was an influx of white powder events throughout the United States. A white powder event is when an unknown white powder is received in the post. More often than not, the attacks do not contain any toxic materials and are carried out for the sole purpose of causing terror and damaging infrastructure. Since these attacks, the FBI and US Postal Service have responded to thousands of white powder events.
Automation > Laboratory Instrumentation > White Papers
Characterisation of IgG Monomers and their Aggregates
| By Malvern Panalytical
Whether we are trying to improve candidate formulations or trying to characterize final formulations, knowing exactly what a protein sample comprises and how much we have of each component is of paramount importance.
Automation > Laboratory Instrumentation > White Papers
Evaluating the Rheological Properties of Hyaluronic Acid Hydrogels for Dermal Filler Applications
| By Malvern Panalytical
Hyaluronic acid (HA) is a naturally occurring polysaccharide frequently used as a functional ingredient in many topical and subcutaneous anti-ageing treatments such as dermal fillers, which exploit the polymer’s unique viscoelastic properties for effective soft tissue augmentation. When administered subcutaneously, HA builds an elastic network within wrinkles and rhytides to give the skin a plumper and fuller look.
Automation > Laboratory Instrumentation > White Papers
Characterisation of Pollen Samples with the Morphologi® G3SE
| By Malvern Panalytical
Some of the most frequent inhalant allergens from the natural environment are present in pollen grains and a wide range of pollen source material is used in the production of immunotherapy or diagnostic products as well as in allergy research.
Automation > Laboratory Instrumentation > White Papers
91-105 of 240 results