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Laboratory Instrumentation White Papers

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1-15 of 224 results
SYSTAG: The use of FlexyPAT-HFC for calorimetric measurements
| By SYSTAG
FlexyPAT is a modular Process Automation Technology that enables automated customer-specific lab reactor systems to be implemented in a very cost-effective manner, including with the integration of existing devices.
Automation > Laboratory Instrumentation > White Papers
SYSTAG: Efficient synthesis development
| By SYSTAG
Efficient synthesis development using the example of determi-nation of the metastable zone.
Automation > Laboratory Instrumentation > White Papers
Top tips for avoiding particle sizing failures with your laser diffraction method
| By Malvern Instruments
Particle size defines the performance of a wide range of different products, including cement, paints, inks, metal powders, cosmetics, foods and drinks. Measuring relevant particle size data is therefore essential in many industries, with laser diffraction usually the technique of choice. Fast, highly automated and suitable for measurement across a broad size range, 0.01 to 3500 microns, modern laser diffraction systems have reduced particle sizing to a matter of sample loading and push button operation, providing that a suitable method is in place.
Automation > Laboratory Instrumentation > White Papers
Analytical characterisation of mouthfeel in chocolate
| By Malvern Instruments
The particle size and rheology of the chocolate are critical factors in determining and predicting mouthfeel.
Automation > Laboratory Instrumentation > White Papers
Biophysical application of calorimetric methods to protein misfolding and aggregation examinations
| By Malvern Instruments
Unfolded proteins fold into thermodynamically-favorable native structures under the correct physiological conditions for gain of function (Figure 1) [1-4]. The burial of hydrophobic regions in a protein's interior, along with the exposure of hydrophilic residues to aqueous solutions stabilizes native structures and ensures solubility. Active native proteins perform their biological functions through highly regulated intermolecular interactions with their binding partners, under thermodynamic control.
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments: Assessing Fuel Filter Efficiency using Online Laser Diffraction
| By Malvern Instruments
Meeting requirements for ISO16332: Standard method for evaluating fuel/water separation efficiency in diesel engines.
Automation > Laboratory Instrumentation > White Papers
Top 10 Factors to Consider When Selecting a Dynamic Light Scattering (DLS) Instrument
| By Malvern Instruments
The physical components and features of a dynamic light scattering (DLS) instrument along with the instrument's technical specifications are obviously important considerations when purchasing a new system.
Automation > Laboratory Instrumentation > White Papers
FlexyPlant – Scale-Up Application Example from the Pharmaceutical Industry
| By SYSTAG
Scale-up by a factor of 300; from 70ml reactor into 25lt pilot plant. A scale-up step by factor 300 takes place in different laboratories, in fully diversified plants mostly. A great deal of information may be lost, and the knowledge of development Chemists can not be implemented optimally.
Automation > Laboratory Instrumentation > White Papers
Optimizing Development Resources for Efficient Product Development
| By SYSTAG
Nowadays, efficient process research and development are, more than ever, an absolute must for contract manufacturers and API manufacturers. New products/processes need to be pushed through to market readiness faster and faster.
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments: Exploring the impact of particle characteristics on suspension rheology
| By Malvern Instruments
How particle size, shape and zeta potential influence suspension rheology. Many products are suspensions or dispersions of particles in a liquid medium. Examples range from adhesives, ceramics, paints and inks through to foods, drinks, personal care products and medicines. The physical properties of the dispersed particles in such systems, including particle size, particle size distribution, concentration, electric charge (zeta potential), and even particle shape, can all strongly influence the overall (bulk) rheological properties of a suspension, thereby defining product behavior and functionality. Understanding these interactions is crucial when it comes to achieving desirable product performance, whether it be a stable paint or medicine, workable cement, or a visually appealing shower gel or drink. This white paper examines the impact of particle properties on suspension viscosity, and more broadly on rheological behavior. It looks in some detail at how particle size, shape and zeta potential influence critical aspects of suspension performance such as viscosity and stability and how these properties can be manipulated to tailor this behavior.
Automation > Laboratory Instrumentation > White Papers
The new MicroCal PEAQ-DSC Automated System
| By Malvern Instruments
Eight reasons to upgrade from the MicroCal VP-Capillary DSC system. Use of Differential Scanning Calorimetry (DSC) in biopharmaceutical development. Differential scanning calorimetry (DSC) is an established biophysical tool for protein stability characterization during biopharmaceutical drug development. DSC data are used to advance the most stable and 'developable' proteins into the pipeline, and optimize the process and formulation conditions to maintain protein stability during manufacturing and storage.
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments Discusses GPC/SEC Analysis of Polymer Solutions Used in Inkjet Printing
| By Malvern Instruments
Inkjet printing of polymer solutions is an area of interest for depositing precise, high-throughput patterns of functional polymer. The applications of the polymer patterns include OLEDs, organic circuits, and textiles. The efficacy of this printed pattern can be negatively impacted by the concentration and viscosity of the polymer solution, the molecular weight and molecular weight distribution of the polymer, and level of branching in the polymer. Therefore, it is of keen interest to understand the effect of inkjet printing on the degradation of polymers. In this application note, the molecular weight (MW) and molecular weight distribution (MWD) of various polymers is shown as a function of time during inkjet printing. The data shown in this application note is from references [1-2].
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments: Gold Nanoparticle Applications and Characterization by Nanoparticle Tracking Analysis
| By Malvern Instruments
This work is a review of nanoparticle size and concentration analysis in gold colloid applications. Gold nanoparticles are one of the most popular and extensively researched type of nanoparticle. A Google Scholar search of the term "gold nanoparticles" results in over 500,000 hits. Applications range from the biological to the material, and include nanomedicine, drug delivery, cancer diagnostics, biological scaffolds, biosensors, contrast agents, catalysts, and CMP slurries for the manufacturing of microprocessor [1].
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments compares metal powders from different atomization processes using automated image analysis
| By Malvern Instruments
Image analysis is an ideal tool for characterizing the size and shape distributions of atomized metal powders. The manufacture of complex shaped metal parts by Metal Injection Molding (MIM) is a growing industry. The shape and size of metal powders play an important role in determining process efficiency and properties of the final MIM components. Spherical powder particles are typically favored by MIM manufacturers looking to achieve best tolerances and properties in final components. Therefore, it is important to monitor atomized powder to ensure that particles of the desired shape and size are produced.
Automation > Laboratory Instrumentation > White Papers
1-15 of 224 results