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Laboratory Instrumentation White Papers

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1-15 of 174 results
Evaluation of the BioFlo® 320 Process Capabilities
| By Eppendorf
This poster characterizes the capabilities of the BioFlo320 in terms of key process parameters including oxygen transfer rate (OTR), volumetric mass transfer coecient (kLa), tip speed, mixing time, and water consumption. These data enable quantitative analyses of bioprocess engineering parameters, thus allowing potential users to gain insight into the system’s cell culture and fermentation capabilities.
Automation > Laboratory Instrumentation > White Papers
Taking the Strain
| By Eppendorf
Today, the rapidly expanding demand for vaccine products for viral diseases such as rabies has necessitated the development of more sophisticated production techniques based around cell culture systems. This article reviews vaccine production strategies, with a focus on rabies, looking specifically at the use of the Vero cell line - used worldwide and approved by the US Food and Drug Administration - as well as media technology and the bioreactor options available.
Automation > Laboratory Instrumentation > White Papers
Analytical Strategies for Ink Formulation
| By Malvern Instruments
Controlling the performance of an ink is a complex optimization challenge. Understanding how features of the system, the dispersed particle size in particular, impact stability and behavior during each stage of the printing process is crucial for effective formulation. This white paper offers practical guidance on using a range of analytical techniques, including rheology, and particle size and zeta potential measurement to generate the required knowledge.
Automation > Laboratory Instrumentation > White Papers
Carbon and Carbon Nanotube Characterization by Nanoparticle Tracking Analysis
| By Malvern Instruments
This white paper discusses examples where Nanoparticle Tracking Analysis is helping to understand these carbon-based nanostructures.
Automation > Laboratory Instrumentation > White Papers
Viruses and Viral Vaccines: Characterization by Nanoparticle Tracking Analysis
| By Malvern Instruments
NTA utilizes the properties of both light scattering and Brownian motion in order to obtain the particle size distribution of samples in liquid suspension. A laser beam is passed through the sample chamber, and the particles in suspension in the path of this beam scatter light in such a manner that they can easily be visualized via a 20x magnification microscope onto which is mounted a camera.
Automation > Laboratory Instrumentation > White Papers
Understanding Taylor Dispersion Analysis
| By Malvern Instruments
Taylor Dispersion Analysis (TDA) is a microcapillary flow-based technique whereby a nanoliter-scale sample pulse is injected into the laminar flow of run buffer, which then spreads out axially due to the combined actions of convection and radial diffusion. Detection of the equilibrium concentration profile (or Taylorgram) of the dispersed sample pulse allows the molecular diffusion coefficient and hence hydrodynamic radius of solute molecules to be calculated.
Automation > Laboratory Instrumentation > White Papers
Extending the Boundaries of QbD
| By Malvern Instruments
The last decade has seen a shift within the pharmaceutical industry towards a design space approach to development and manufacture, an agenda underpinned by ICHQ8, Q9 and Q10 and the concept of Quality by Design (QbD). However, because a design space approach naturally focuses attention on the areas of a project that are potentially the most vulnerable to failure it has broader value for risk management.
Automation > Laboratory Instrumentation > White Papers
Measuring Environmental Impact of Nanomaterial Wastes and Contaminants Using Nanoparticle Tracking Analysis
| By Malvern Instruments
The increasing number of nanomaterial based consumer products raises concerns about their possible impact on the environment. Suitable methods for their analysis are a particular problem in this regard. This white paper reviews the use of Nanoparticle Tracking Analysis (NTA) in addressing this need.
Automation > Laboratory Instrumentation > White Papers
Assessing Nanoparticle Toxicity in Waste Water using Nanoparticle Tracking Analysis
| By Malvern Instruments
At the same time as an increasing interest in, and rapid development of, a wide range of materials and products containing nanoscale structures and engineered nanoparticles, awareness has grown that the longer term potential toxic effects of such materials and their potential environmental impact are poorly understood. Existing methods have been assessed and new methods sought by which such materials could be analyzed on a routine basis during development and manufacture.
Automation > Laboratory Instrumentation > White Papers
Growing Potential: mAb Production With Fibra-Cel
| By Eppendorf
The market for monoclonal antibodies continues to grow steadily, but there are still bottlenecks in the development of new products, including long development times mostly due to R&D. Advanced bioprocess equipment that meets the specific demands of mAb-producing hybridoma can accelerate design and production, and reduce overall development costs along the way.
Automation > Laboratory Instrumentation > White Papers
DoE Bioprocess Development
| By Eppendorf
Eppendorf DASware is the effective route to design of experiments (DoE) in early-stage bioprocess development. Claudia M Huether-Franken and Sebastian Kleebank explain how the design software applies DoE to DASGIP parallel bioreactor systems.
Automation > Laboratory Instrumentation > White Papers
Specialised Project & Technology Transfer- Laboratory Equipment & Automated Systems
| By SHL Group
A US-based company dedicated to developing intelligent inspection solutions and equipment for the biotechnology, pharmaceutical, and medical device industries wanted to partner with an established manufacturer, possessing design and engineering capabilities as well as appropriate in-house quality systems. With lab equipment that finds defects in medical syringes, vials, cartridges, test tubes, and other medical containers, it was vital for the manufacturing partner to have ISO13485 and ISO9001 quality systems in place.
Automation > Laboratory Instrumentation > White Papers
Design-To-Build – Laboratory Handling Equipment
| By SHL Group
A leading high-end laboratory handling and diagnostics equipment manufacturing company devoted to helping scientists meet challenges regularly faced in the lab, approached SHL Technologies with a request to develop benchtop laboratory tube array handling equipment. This equipment had to be available in a modular set-up and capable of pick-and-place sorting, weight measurement, and barcode reading.
Automation > Laboratory Instrumentation > White Papers
Complex Module Manufacturing – IC testing Devices
| By SHL Group
An established manufacturer of Integrated Circuit (IC) testing equipment from Germany was following a global sourcing initiative and needed to search for a suitable supplier in Asia that had experience in manufacturing and offered strong production capabilities. Sustaining high quality manufacturing in an environment with established quality systems was vital to the manufacturer and became one of the key determining factors when choosing the right supplier.
Automation > Laboratory Instrumentation > White Papers
Specialised Project & Technology Transfer – Precision Neurosurgical Equipment
| By SHL Group
An established manufacturer of Integrated Circuit (IC) testing equipment from Germany was following a global sourcing initiative and needed to search for a suitable supplier in Asia that had experience in manufacturing and offered strong production capabilities. Sustaining high quality manufacturing in an environment with established quality systems was vital to the manufacturer and became one of the key determining factors when choosing the right supplier.
Automation > Laboratory Instrumentation > White Papers
1-15 of 174 results