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Laboratory Instrumentation White Papers

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1-15 of 217 results
FlexyPlant – Scale-Up Application Example from the Pharmaceutical Industry
| By SYSTAG
Scale-up by a factor of 300; from 70ml reactor into 25lt pilot plant. A scale-up step by factor 300 takes place in different laboratories, in fully diversified plants mostly. A great deal of information may be lost, and the knowledge of development Chemists can not be implemented optimally.
Automation > Laboratory Instrumentation > White Papers
Optimizing Development Resources for Efficient Product Development
| By SYSTAG
Nowadays, efficient process research and development are, more than ever, an absolute must for contract manufacturers and API manufacturers. New products/processes need to be pushed through to market readiness faster and faster.
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments: Exploring the impact of particle characteristics on suspension rheology
| By Malvern Instruments
How particle size, shape and zeta potential influence suspension rheology. Many products are suspensions or dispersions of particles in a liquid medium. Examples range from adhesives, ceramics, paints and inks through to foods, drinks, personal care products and medicines. The physical properties of the dispersed particles in such systems, including particle size, particle size distribution, concentration, electric charge (zeta potential), and even particle shape, can all strongly influence the overall (bulk) rheological properties of a suspension, thereby defining product behavior and functionality. Understanding these interactions is crucial when it comes to achieving desirable product performance, whether it be a stable paint or medicine, workable cement, or a visually appealing shower gel or drink. This white paper examines the impact of particle properties on suspension viscosity, and more broadly on rheological behavior. It looks in some detail at how particle size, shape and zeta potential influence critical aspects of suspension performance such as viscosity and stability and how these properties can be manipulated to tailor this behavior.
Automation > Laboratory Instrumentation > White Papers
The new MicroCal PEAQ-DSC Automated System
| By Malvern Instruments
Eight reasons to upgrade from the MicroCal VP-Capillary DSC system. Use of Differential Scanning Calorimetry (DSC) in biopharmaceutical development. Differential scanning calorimetry (DSC) is an established biophysical tool for protein stability characterization during biopharmaceutical drug development. DSC data are used to advance the most stable and 'developable' proteins into the pipeline, and optimize the process and formulation conditions to maintain protein stability during manufacturing and storage.
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments Discusses GPC/SEC Analysis of Polymer Solutions Used in Inkjet Printing
| By Malvern Instruments
Inkjet printing of polymer solutions is an area of interest for depositing precise, high-throughput patterns of functional polymer. The applications of the polymer patterns include OLEDs, organic circuits, and textiles. The efficacy of this printed pattern can be negatively impacted by the concentration and viscosity of the polymer solution, the molecular weight and molecular weight distribution of the polymer, and level of branching in the polymer. Therefore, it is of keen interest to understand the effect of inkjet printing on the degradation of polymers. In this application note, the molecular weight (MW) and molecular weight distribution (MWD) of various polymers is shown as a function of time during inkjet printing. The data shown in this application note is from references [1-2].
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments: Gold Nanoparticle Applications and Characterization by Nanoparticle Tracking Analysis
| By Malvern Instruments
This work is a review of nanoparticle size and concentration analysis in gold colloid applications. Gold nanoparticles are one of the most popular and extensively researched type of nanoparticle. A Google Scholar search of the term "gold nanoparticles" results in over 500,000 hits. Applications range from the biological to the material, and include nanomedicine, drug delivery, cancer diagnostics, biological scaffolds, biosensors, contrast agents, catalysts, and CMP slurries for the manufacturing of microprocessor [1].
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments compares metal powders from different atomization processes using automated image analysis
| By Malvern Instruments
Image analysis is an ideal tool for characterizing the size and shape distributions of atomized metal powders. The manufacture of complex shaped metal parts by Metal Injection Molding (MIM) is a growing industry. The shape and size of metal powders play an important role in determining process efficiency and properties of the final MIM components. Spherical powder particles are typically favored by MIM manufacturers looking to achieve best tolerances and properties in final components. Therefore, it is important to monitor atomized powder to ensure that particles of the desired shape and size are produced.
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments Explores Nanobubble Applications and Characterization
| By Malvern Instruments
Malvern Instruments conducts an in depth review of ultra-fine bubble (nanobubble) applications and characterization examples. The generation, measurement, and applied technologies of so-called nanobubbles or ultra-fine bubbles, with diameter ranging from tens to hundreds of nanometers, are evolving dramatically in recent years. The unique properties of nanobubbles makes them attractive for a number of applications such as facility cleaning, food disinfection, and water treatment, as well as possibilities in fields such as disinfecting food products, pharmaceutical delivery, decontamination, and manufacturing of functional materials. Preliminary market research conducted by the Fine Bubble Industries Association shows the size of the fine bubble business increasing from USD 20 million in 2010 to USD 4.3 billion in 2020.
Automation > Laboratory Instrumentation > White Papers
Synergy of Complementary Nanomaterial Characterization Techniques: NTA+DLS
| By Malvern Instruments
Dynamic Light Scattering (DLS) is a mature and proven technology for nanomaterial characterization. Nanoparticle Tracking Analysis (NTA) is a more recent addition to the spectrum of particle characterization techniques and has many similarities to DLS, leading to some confusion as to their relative capabilities. The broad range of measurement capabilities for each technique is complementary in nature, providing a wealth of valuable information. The differences between the two techniques allow the data from one technology to validate and support the other.
Automation > Laboratory Instrumentation > White Papers
Using the Zetasizer Nano to Optimize Formulation Stability
| By Malvern Instruments
Formulation development is a critical activity for many industries, from pharmaceuticals, to paints and coatings. Indeed, it is estimated that in the UK alone, sales of formulated products amount to some £180 billion per year1. This means that getting formulation ‘right’ is an important goal, with considerable value attached to it. Stability is a crucial attribute for many products with a direct impact on performance, shelf-life, kerb appeal and ultimately, worth. A systematic approach to understanding and developing stability can therefore be extremely helpful in improving the likelihood of success in long-term stability trials and accelerating formulation. The Zetasizer range from Malvern is the world’s most widely used system for nanoparticle, colloid and protein size and zeta potential measurements. In this whitepaper, we examine how these capabilities can be exploited to develop stable dispersions.
Automation > Laboratory Instrumentation > White Papers
Key Considerations when Purchasing an Advanced GPC/SEC System
| By Malvern Instruments
Investing in a new GPC/SEC system is a big decision with many factors to consider. This white paper lists the key items that you should think about when buying a new system and discusses the reasons for their importance. Finally, it discusses what Malvern has to offer in this area.
Automation > Laboratory Instrumentation > White Papers
Going with the Flow: Malvern Instruments' Basic Introduction to Rheology
| By Malvern Instruments
Rheology concerns itself with materials that have aspects of both solids and liquids, and researches the flow and deformation of matter. Malvern Instruments explores this study, and reveals its fundamental in relation to force, deformation and time.
Automation > Laboratory Instrumentation > White Papers
Malvern Instruments Shares its Buyer's Guide to Protein Stability Measurement Platforms
| By Malvern Instruments
As a leader in best practices during biopharmaceutical development, Malvern Instruments sheds light on effective protein stability analysis technologies for the biopharmaceutical industry.
Automation > Laboratory Instrumentation > White Papers
Reliable, Long-range Wireless Sensors for Environmental Monitoring
| By Vaisala pbr
The Vaisala viewLinc Monitoring System tracks environmental conditions wirelessly using Vaisala’s VaiNet wireless devices based on LoRa™* technology. By using a chirp spread spectrum (CSS)* wireless protocol, VaiNet provides robust communication that is extremely reliable over long distances and under harsh, complex and obstructed conditions.
Automation > Laboratory Instrumentation > White Papers
1-15 of 217 results