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Application of Dynamic Light Scattering (DLS) to Protein Therapeutic Formulations:Principles, Measurements and Analysis - 1. Basic Principles

Published 17 November 2014 | By Malvern Instruments

This four-part white paper series examines common issues and questions surrounding the principles, measurements and analysis of DLS data and discusses how to minimise the time required for and increase the accuracy of acquiring and interpreting DLS data during the biotherapeutic development process. Here, in Part One of this series, we provide an overview of the key principles of DLS: theory, correlation statistics, deconvolution algorithms, and the intensity to mass transform.

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Application of Dynamic Light Scattering (DLS) to Protein Therapeutic Formulations:Principles, Measurements and Analysis - 1. Basic Principles