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Malvern Instruments – Pharmaceutical Equipment Supplier News

Malvern Instruments – Pharmaceutical Equipment Supplier

Reviewing a Decade of Online Particle Sizing Zementwerk Berlin GmbH & Co KG (Berlin, Germany) has been using Insitec on-line laser diffraction particle sizing (Malvern Instruments) systems to optimize cement production for more than a decade.
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Laser-diffraction particle sizing pays dividends for wet-process monitoring In this article, we take a look at how, from the starting point of an appropriate wet sensor, laser diffraction systems can be engineered to deliver to the needs of different process applications. A case study involving the control of an emulsification unit for the production of oil and water emulsions illustrates what can be achieved and the benefits delivered.
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Setting a benchmark: Using rheology to define the performance of personal care products Products, quality is often defined by a range of functional and sensory attributes, some of which may be easily measured - such as color - and others which may not. Visual or textural appearance and ease of application exemplify properties in this second category. Ultimately these attributes are assessed subjectively via user feedback, but relying on such information to guide formulation is somewhat impractical, particularly in the early stages of product development. Metrics that reliably correlate with product performance are therefore essential.
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Using Taylor Dispersion Analysis to determine oligomeric state of insulin Taylor dispersion analysis is an emerging biophysical characterization technique that offers unique benefits in the early stages of biopharmaceutical development – providing answers that established techniques cannot effectively handle.
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Food Safety and Quality: Sizing Up Particles Particle size analysis is important in many industries. Knowledge of particle size is important in the food industry because it affects the production and handling of ingredients and the formulation, processing, and quality control of food and beverage products. Particle size affects reactivity, solubility, and flowability of ingredients and the texture, mouthfeel, and processing of products.
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Using Laser Diffraction to Measure Particle Size and Distribution of Metal Powders How laser diffraction fulfils the metal powder industry’s requirements for accurate particle size information.
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Sizing dairy emulsions for optimal performance Sarennah Longworth-Cook, Product Technical Specialist, Malvern Instruments
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Using rheology to optimize the performance of EOR fluids Chemical enhanced oil recovery (EOR) using techniques such as polymer flooding can extract an additional 20% of the oil remaining in a reservoir following primary and secondary recovery. This article describes work carried out at TU Clausthal, Germany, to rheologically characterize polymer solutions for EOR applications. Understanding how any given solution flows and interacts with the pore geometry of the reservoir is the key to achieving beneficial performance.
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Chewing the Fat: Using Rheology to Monitor Food Changes During Mastication A study of how matter behaves under the interrelating influences of force, deformation, and time, rheology is utilised by Dr Steve Carrington of Malvern Instruments and Prof. D. J. McClements of the University of Massachusetts to monitor how food changes whilst being chewed.
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Malvern Instruments Reveals how Combined DLS/Raman Provides New Molecular Insights of Complex Fluids In particular, Malvern's article demonstrates the correlation between molecular changes (Raman Spectroscopy) and microstructural evolution of rheological properties (DLS, DLS-optical microrheology) for the first time for surfactant-based wormlike micellar system.
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The new Zetasizer AT – Automated Online Nanoparticle Sizing For Process Monitoring Malvern Instruments has launched the new Zetasizer AT, a robust, online, automated analyzer that uses dynamic light scattering (DLS) to automatically measure the size of nanoparticles in suspensions and emulsions.
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Oxford Researcher Explains Central Role of Microcalorimetry in Meningitis Vaccine Development In a webinar presentation entitled the ‘Application of DSC to structural studies on meningitis vaccines’, which is now freely available on the Malvern Instruments’ website, Dr David Staunton, Lecturer in Biochemistry at the University of Oxford (UK), explains why he recommends the use of Differential Scanning Calorimetry (DSC) as a first line technique when characterizing recombinant proteins. Reviewing DSC alongside other methods used for protein characterization, including thermal shift techniques, Dr Staunton examines the advantages and limitations of each.
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New Tools for Biopharma Development Take Center Stage on the Malvern AAPS 2015 Booth New tools from Malvern that answer to specific analytical challenges in biopharma development will take center stage at this year’s AAPS Annual Meeting and Exposition, in Orlando, USA (Orange County Convention Center, 25 - 29 October 2015). Alongside Malvern’s established analytical suite for both large and small molecule development will be a range of complementary and orthogonal characterization technologies with proven value for accelerating innovator and generic product development.
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Malvern Instruments Establishes new Biopharmaceutical Applications Laboratory in the Heart of San Diego's Biotech Community Malvern Instruments has established a new biopharmaceutical applications laboratory in the heart of San Diego’s biotechnology cluster. The new laboratory will enable customers and Malvern applications specialists alike to experience and use Malvern’s range of specialist biophysical characterization systems in a working biopharmaceutical environment.
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A Fruitful Approach to Polysaccharide Characterization… CP Kelco Reveals how GPC/SEC Supports its Manufacture of High Performance Biopolymers nsight from CP Kelco, a global leader in the specialty hydrocolloids market, provides a blueprint for the intelligent, cost-efficient deployment of gel permeation/size exclusion chromatography (GPC/SEC) in biopolymer manufacture.
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Resolve Challenges, Find Solutions: Join Malvern for Expert Help on Protein Interaction Analysis with MicroCal PEAQ-ITC At the 29th Annual Symposium of The Protein Society (22-25th July, Barcelona, Spain) Natalia Markova, Principal Scientist- MicroCal, Malvern Instruments, will be presenting a workshop on how to enable high resolution protein interaction analysis using the latest MicroCal PEAQ-ITC system. Studies of biomolecular interactions are fundamentally important in all areas of the life sciences since such interactions drive and regulate all biological processes.
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Expert Presentations and Practical Demonstrations Impress Nanoparticle Characterization Seminar Attendees A series of highly interactive 2-day seminars delivered by Malvern Instruments, which encompassed expert presentations and 'up close' practical workshops showcasing the latest in nanoparticle characterization technology, have been widely praised by attendees.
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A Dynamic Approach to Educating Industry-Ready Nanotechnology Technicians Seattle’s Hub for Industry-Driven Nanotechnology Education (Seattle, USA), an imaginative educational body with a flexible and highly productive model for nanotechnician training, has identified dynamic light scattering particle sizing as an essential analytical technique, investing in a Zetasizer Nano from Malvern Instruments.
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Viscosizer TD: A New Automated Tool for Biophysical Characterization Malvern Instruments has launched a new system based around Taylor Dispersion Analysis (TDA) to provide researchers with a novel orthogonal technique to accelerate biopharmaceutical drug candidates through the development pipeline. The Viscosizer TD speeds up stability and formulation studies by offering unique solution-based molecular sizing capabilities, combined with relative viscosity measurement.
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Introducing the new Zetasizer WT - automatic, online monitoring for stable and cost-effective water treatment A newly launched, innovative online zeta potential analyzer for water treatment allows water plant operators to control coagulation processes with enhanced levels of accuracy and confidence. The Zetasizer WT from Malvern Instruments is a fully automated analyzer that continuously monitors the properties of water during coagulation to provide precise and reliable data for optimizing chemical dosage levels. Delivering absolute (no calibration), highly sensitive analysis the new system enables a proactive response to changes in the process, enhancing plant stability and reducing the risk of significant events.
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‘Unsurpassed Protein SEC’: OMNISEC Delivers Accurate Information with Minimal Sample In a new webinar ‘Unsurpassed protein SEC using the latest innovation in advanced detection, OMNISEC’, experts from Malvern Instruments demonstrate how the OMNISEC size exclusion chromatography (SEC) system supports efficient screening early in the drug development pipeline by enabling precise characterization with minimal sample volumes.
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Ohio State University Researchers use Nanoparticle Tracking Analysis (NTA) in NIH-Funded Project Examining Targeted Delivery of microRNA-loaded Microvesicles for Cancer Therapy Researchers in the Department of Chemical and Biomolecular Engineering at The Ohio State University (Columbus, Ohio, USA) are using Malvern Instruments’ NanoSight Nanoparticle Tracking Analysis (NTA) to study extracellular vesicle yields from different cell culture lines.
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Malvern Reveals New Advances in Interfacial Measurement Techniques At upcoming events in the colloids conference calendar, physicists from Malvern instruments will reveal new advances in the measurement of interfacial interactions that directly support the control of industrial product performance. The advances center on the measurement of zeta potential, a parameter that quantifies the attractive/repulsive forces between particles, or between a particle and a surface. The resulting data can be used to inform product development in industries including cosmetics, agrochemicals and pharmaceuticals.
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Malvern Puts the Spotlight on Cutting Edge Analytical Strategies at ISFRS 2015 At the 7th International Symposium on Food Rheology and Structure (7 – 10th June, Zurich, Switzerland), experts from Malvern Instruments will be presenting new research showing how innovative measurement and analytical strategies enabled by the company’s instruments can help to drive successful food formulation.
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Second Edition of Popular Nanoparticle Characterisation Book Adds more Research Reviews A brand new online edition of a highly popular book that reviews third party papers on the applications and usage of Nanoparticle Tracking Analysis (NTA) is now available from Malvern Instruments. Updated for 2015 this latest edition reviews the first 1000 reports of the applications and usage of NTA and supersedes the original 2013 publication. The book is intended to enable readers to keep abreast of work being done in a variety of different fields and to provide Malvern NanoSight NTA users with insight into the work of others who are using the technology.
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Malvern Instruments to Showcase an Expanding Rheological Toolkit at AERC 2015 At the 10th Annual European Rheology Conference (AERC) - Cité des Congrès, Nantes, France, 14-17 April 2015 - Malvern Instruments will showcase an expanding range of rheological tools for enhancing research, and understanding and optimising product performance.
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Exceptional Sensitivity of the new OMNISEC GPC/SEC System Excites Attendees at SCM-7 The ground-breaking sensitivity of Malvern Instruments’ new OMNISEC gel permeation chromatography/size exclusion chromatography system generated significant excitement from scientists meeting at the Seventh International Symposium on the Separation and Characterization of Natural and Synthetic Macromolecules (SCM-7), when the system made a well-received debut late in January.
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Analytical Strategies That Support OSD Formulation: A new Whitepaper from Malvern Instruments A new whitepaper from Malvern Instruments provides detailed guidance on the analytical technologies that help to accelerate oral solid dosage (OSD) product formulation to a successful conclusion. 'Analytical techniques with a place in the oral solid dosage formulation toolkit' reviews the regulatory and QbD framework associated with OSD formulation and demonstrates how Malvern systems can be used to generate the data required.
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Malvern’s new OMNISEC GPC/SEC Platform Brings Ground-Breaking Performance to the Analysis of Polymers, Proteins and other Macromolecules A completely new gel permeation/size exclusion chromatography (GPC/SEC) platform from Malvern Instruments breaks new ground in delivering the high performance, ease of use and productivity demanded in today’s analytical laboratories. Malvern’s innovative OMNISEC platform integrates highly efficient sample separation via the OMNISEC RESOLVE module and high sensitivity analysis using OMNISEC REVEAL, a fully integrated multi-detector array. The system has applications wherever there is a need for detailed analysis and understanding of natural or synthetic polymers, proteins and macromolecules.
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Malvern to Show new Analytical Systems at Pittcon 2015 and Present Five Educational Short Courses As part of its rapidly expanding range of analytical tools for materials characterization, Malvern Instruments will showcase a new chromatography system and detectors at Pittcon 2015 (Mar 8th – 12th, New Orleans, USA). New additions to Malvern’s recently acquired MicroCal microcalorimetry range will also be on display.
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