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news.Roche NimbleGen and BGI have developed a Major Histocompatibility Complex (MHC) region capture technology.
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MHC is a large cluster of genes found on the short arm of chromosome 6 including 150 expressing genes which progresses diseases like AIDs, arteriosclerosis, cancers, diabetes and leukemia.
The new technology is based on NimbleGen’s revolutionary process for the enrichment of the MHC region – SeqCap EZ Choice Library.
MHC region capture technology targets the traditional MHC region (3.37MB) and also approximately 1.6Mb of the regions surrounding MHC, providing a total of 4.97Mb (chr6: 28477797-33448354) and includes 8 known haplotypes.