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Laboratory Instrumentation

Cepheid, pharma firms collaborate on diagnostic test for multidrug-resistant bacterial infections By PBR Staff Writer
Cepheid has entered into a new collaboration with AstraZeneca, Cubist and GSK to encourage transformational change in infectious disease therapy.
Automation > Laboratory Instrumentation > News
BioLight announces start of clinical study with DiagnosTear dry eye syndrome diagnostic assay BioLight Life Sciences Investments announced that DiagnosTear has received all necessary approvals from Sheba Medical Center near Tel Aviv to begin a clinical study with its TeaRx, point-of-care Dry Eye Syndrome diagnostic assay. DiagnosTear is part of BioLight’s XLVision Sciences ophthalmology cluster.
Automation > Laboratory Instrumentation > News Hepregen launches first application-oriented in vitro kit By PBR Staff Writer
Bioengineered micro-liver platforms developer Hepregen has launched its first application-oriented in vitro kit, called Human HepatoPac, for identification and profiling of drug metabolites.
Automation > Laboratory Instrumentation > News
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How can Nanoparticle Tracking Analysis Assist in the Production of Nanoparticles
| By Malvern Instruments
This white paper highlights the growth in the use of the technique of Nanoparticle Tracking Analysis as applied to nanoparticles and nanomaterials production and analysis, from the very first reports on nanoscale silver and gold (Lundahl et al. (2008) and Marsh et al. (2008), respectively).
Automation > Laboratory Instrumentation > White Papers
Zeta Potential Measurements of High Conductivity Colloidal Samples
The diffusion barrier technique is a measurement method that was originally developed for the prevention of protein denaturation during zeta potential measurements with Zetasizer Nano instruments [1-3].
Automation > Laboratory Instrumentation > Case Studies
Characterisation of Fiber-Like Bacteria on the Morphologi G3 with the Wet Cell Accessory
Trichodesmium is a globally significant genus of filamentous cyanobacteria (bluegreen algae) that inhabits warm waters in the tropical oceans. Ecologists and biologists are interested in researching the morphological growth of this organism to better understand how it acquires and uses nutrients such as phosphorus and micronutrient iron, which are often in short supply.
Automation > Laboratory Instrumentation > Case Studies
Haselmeier announces the launch of INSUPen® EZ in India by Biocon
Haselmeier announces that Biocon, one of Asia’s premier biotechnology companies, has just launched INSUPen® EZ in India. The INSUPen EZ is a second generation pen and follows on the success of Biocon’s premier insulin delivery device INSUPen®. Under the terms of the agreement between the two companies, Biocon has worldwide distribution rights to INSUPen® EZ, for use with Biocon’s insulin, Basalog™ and Insugen™, and insulin analogues.
Automation > Laboratory Instrumentation > Press Releases
Malvern exhibits MicroCal and NanoSight Brands Alongside New Mastersizer and Zetasizer Products at AAPS 2014
Company showcases rapidly growing portfolio of analytical solutions for pharma and biopharma applications.
Automation > Laboratory Instrumentation > Press Releases
Malvern Manager Award Marks Almost Two Decades of Service on the Powtech Advisory Committee
For Malvern Instruments marketing manager Mrs Renate Hessemann, this year's Powtech exhibition in Nürnberg, Germany (30 Sep-2 Oct 2014), was her last as a member of the Powtech advisory committee on which she has served for almost 20 years. In recognition of this long commitment, she was presented with a special award at a meeting held on the eve of the show opening.
Automation > Laboratory Instrumentation > Press Releases
Studying Low-Affinity Fragments of Ligands by ITC
| By Malvern Instruments
Molecular recognition is a fundamental prerequisite to all biological processes from enzymatic catalysis to signal transduction. The modern pharmaceutical industry is built upon the concept of selective intervention in such systems (1). Furthermore, similar concepts are being implemented, through supramolecular chemistry, to develop novel smart materials, components for nanotechnology and molecular electronics (2). If we are to harness the full potential of molecular recognition, it is essential that we understand the subtle interplay between structure and thermodynamics in complex formation.
Automation > Laboratory Instrumentation > White Papers
Pharmaceutical Excipient Characterisation
| By Malvern Instruments
The aim of formulation development is to design a product and its manufacturing process to consistently deliver the intended Quality Target Product Profile (QTPP). This involves determining the Critical Quality Attributes (CQAs) for the Active Pharmaceutical Ingredient (API) and excipients that define the performance of the product. These are generally identified through an assessment of the extent to which the variation in a specific attribute, for example particle size, can impact the drug product’s quality and performance.
Automation > Laboratory Instrumentation > White Papers
Differentiation and Characterisation of Subvisible Particulates in Therapeutic Protein Products
| By Malvern Instruments
The formation of protein aggregates is a particular concern for parenteral administration biopharmaceuticals due to the potential for increased immunogenicity. As a consequence, there is an expectation from regulatory agencies for companies to monitor and, if required, reduce the levels of sub-visible particles present in therapeutic protein from manufacture through their complete shelf life.
Automation > Laboratory Instrumentation > White Papers
Revealing Kinase Inhibitor Mechanisms: ITC Leads the Way
| By Malvern Instruments
The kinome of an organism is the set of protein kinases in its genome and these protein-modifying enzymes are potential targets in a number of therapeutic areas. Studies to characterise the human kinome, together with the explosion of available kinase crystal structures over recent years, have led to an increased focus on kinases as potential targets for pharmaceutical intervention.
Automation > Laboratory Instrumentation > White Papers
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